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Cristina Santoro: Curriculum Vitae in Ematologia

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Il presente documento riassume il curriculum vitae di Cristina Santoro, specialista nel campo dell'ematologia.

Formazione Universitaria e Specializzazione

Cristina Santoro ha svolto la sua formazione universitaria presso l'Università Policlinico Umberto I di Roma.

Esperienza Professionale

  • Assegnista di ricerca: Da febbraio 2009 a febbraio 2012 ha lavorato come assegnista di ricerca presso il Policlinico Umberto I, Roma.
  • Attività di ricerca all'estero: Ha svolto attività di ricerca presso il Department of Pediatrics, Hemophilia Program al College, NY, sotto la direzione del Prof.

Capacità e Competenze

Cristina Santoro possiede le seguenti capacità e competenze:

  • Capacità sociali: Buono spirito di gruppo e ottime capacità di comunicazione.
  • Capacità organizzative: Buone capacità organizzative sia nell’ambito dell’attività clinica che di ricerca.

Progetti di Ricerca

Ha partecipato a progetti come INSIGHT/RISE, promossi dal Dpt. Academic Medical Center, Amsterdam, the Netherlands, sotto l’egida di tale Società Scientifica.

Pubblicazioni Scientifiche

Cristina Santoro è autrice e co-autrice di numerose pubblicazioni scientifiche su riviste internazionali nel campo dell'ematologia. Di seguito alcuni esempi:

  1. Acquila M, Pasino M, Santoro C, Lanza T, Molinari AC, Bottini F, Bicocchi MP. Germ-line origin of intron 1 inversion in two haemophilia A families. Haemophilia.
  2. Mazzucconi MG, Redi R, Bernasconi S, Bizzoni L, Dragoni F, Latagliata R, Santoro C, Mandelli F. A long-term study of young patients with essential thrombocythemia treated with anagrelide. Haematologica.
  3. L. Bizzoni, M.G. Mazzucconi, M. Gentile, C. Santoro, S. Bernasconi, F. Chiarotti, R. Foà and F. Mandelli . Idiopathic thrombocytopenic purpura (ITP) in the elderly: clinical course in 178 patients. Eur J Haematol.
  4. Giona F, Palumbo G, Amendola A, Santoro C, Mazzuconi MG. Platelet function and coagulation abnormalities in type 1 Gaucher disease patients: effects of enzyme replacement therapy (ERT). J Thromb Haemost.
  5. Valerio De Stefano, Tommaso Za, Elena Rossi, Elena Elli, Alessandro M. Vannucchi, Marco Ruggeri, Caterina Micò, Nicola Vianelli, Rossella R. Cacciola, Alessia Tieghi, Cristina Santoro, Enrico M. Pogliani, Paola Guglielmelli, Lisa Pieri, Francesca Scognamiglio, Francesco Rodeghiero, Guido Finazzi, Luigi Gugliotta, Giuseppe Leone, Tiziano Barbui, for the GIMEMA CMD-Working Party. Recurrent Venous Thrombosis in patients with Policythemia Vera and Essential Thrombocythemia.
  6. Ruggeri M, Rodeghiero F, Tosetto A, Castaman G, Scognamiglio F, Finazzi G, Delaini F, Micò C, Vannucchi AM, Antonioli E, De Stefano V, Za T, Gugliotta L, Tieghi A, Mazzucconi MG, Santoro C, Barbui T; Gruppo Italiano Malattie Ematologiche dell'Adulto (GIMEMA) Chronic Myeloproliferative Diseases Working Party. Postsurgery outcomes in patients with polycythemia vera and essential thrombocythemia: a retrospective survey. Blood. 2008;111(2):666-71.
  7. Santoro C, Rago A, Biondo F, De Propris MS, De Vellis A, Guarini A, Pignoloni P, Mazzucconi MG. Efficacy of rituximab treatment in postpartum acquired haemophilia A. Haemophilia.
  8. De Stefano V, Za T, Rossi E, Vannucchi AM, Ruggeri M, Elli E, Micò C, Tieghi A, Cacciola RR, Santoro C, Gerli G, Vianelli N, Guglielmelli P, Pieri L, Scognamiglio F, Rodeghiero F, Pogliani EM, Finazzi G, Gugliotta L, Marchioli R, Leone G, Barbui T; GIMEMA CMD-Working Party. Recurrent thrombosis in patients with polycythemia vera and essential thrombocythemia: incidence, risk factors, and effect of treatments. Haematologica. 2008;93(3):372-80.
  9. Tagliaferri A, Franchini M, Coppola A, Rivolta GF, Santoro C, Rossetti G, Feola G, Zanon E, Dragani A, Iannaccaro P, Radossi P, Mannucci PM. Effects of secondary prophylaxis started in adolescent and adult haemophiliacs. Haemophilia. 2008;14(5):945-51.
  10. Franchini M, Coppola A, Molinari AC, Santoro C, Schinco P, Speciale V, Tagliaferri A. Forum on: the role of recombinant factor VIII in children with severe haemophilia A. Haemophilia. 2009;15(2):578-86.
  11. Santoro C, Iorio A, Ferrante F, Pallotta A, Pignoloni P, Biondo F, Agnelli G, Mazzucconi MG. Performance of recalibrated ReFacto laboratory standard in the measurement of FVIII plasma concentration via the chromogenic and one-stage assays after infusion of recalibrated ReFacto (B-domain deleted recombinant factor VIII). Haemophilia. 2009;15(3):779-87.
  12. Tagariello G, Iorio A, Santagostino E, Morfini M, Bisson R, Innocenti M, Mancuso ME, Mazzucconi MG, Pasta GL, Radossi P, Rodorigo G, Santoro C, Sartori R, Scaraggi A, Solimeno LP, Mannucci PM; Italian Association Hemophilia Centre (AICE).Comparison of the rates of joint arthroplasty in patients with severe factor VIII and IX deficiency: an index of different clinical severity of the 2 coagulation disorders. Blood. 2009;114(4):779-84.
  13. De Stefano V, Za T, Rossi E, Vannucchi AM, Ruggeri M, Elli E, Micò C, Tieghi A, Cacciola RR, Santoro C, Vianelli N, Guglielmelli P, Pieri L, Scognamiglio F, Cacciola E, Rodeghiero F, Pogliani EM, Finazzi G, Gugliotta L, Leone G, Barbui T; for the GIMEMA Chronic Myeloproliferative Neoplasms Working Party. Increased risk of recurrent thrombosis in patients with essential thrombocythemia carrying the homozygous JAK2 V617F mutation.
  14. Latagliata R, Rago A, Spadea A, Santoro C, Carmosino I, Breccia M, Napoleone L, Fama A, Biondo F, Volpicelli P, Vozella F, Stefanizzi C, Petti MC, Alimena G, Mazzucconi MG. Decisional flow with a scoring system to start platelet-lowering treatment in patients with essential thrombocythemia: long-term results.
  15. De Stefano V, Za T, Rossi E, Vannucchi AM, Ruggeri M, Elli E, Micò C, Tieghi A, Cacciola RR, Santoro C, Gerli G, Guglielmelli P, Pieri L, Scognamiglio F, Rodeghiero F, Pogliani EM, Finazzi G, Gugliotta L, Leone G, Barbui T. Leukocytosis is a risk factor for recurrent arterial thrombosis in young patients with polycithemia vera and essential thrombocythemia.
  16. Coppola A, Santoro C, Tagliaferri A, Franchini M, DI Minno G. Understanding inhibitor development in haemophilia A: towards clinical prediction and prevention strategies. Haemophilia. 2010;16 Suppl 1:13-9.
  17. Tagliaferri A, Rivolta GF, Iorio A, Oliovecchio E, Mancuso ME, Morfini M, Rocino A, Mazzucconi MG, Franchini M; Italian Association of Hemophilia Centers, Ciavarella N, Scaraggi A, Valdrè L, Tagariello G, Radossi P, Muleo G, Iannaccaro PG, Biasoli C, Vincenzi D, Serino ML, Linari S, Molinari C, Boeri E, La Pecorella M, Carloni MT, Santagostino E, Di Minno G, Coppola A, Rocino A, Zanon E, Spiezia L, Di Perna C, Marchesini M, Marcucci M, Dragani A, Macchi S, Albertini P, D'Incà M, Santoro C, Biondo F, Piseddu G, Rossetti G, Barillari G, Gandini G, Giuffrida AC, Castaman G.Mortality and causes of death in Italian persons with haemophilia, 1990-2007.Haemophilia. 2010;16(3):437-46.
  18. Santoro C, Rago A, Biondo F, Conti L, Pulcinelli F, Laurenti L, Perrone MP, Baldacci E, Leporace A, Mazzucconi MG. Prevalence of allo-immunization anti-HLA and anti-integrin alphaIIbbeta3 in Glanzmann Thromboasthenia patients. Haemophilia. 2010;16(5):805-12.
  19. Santoro C, Goldberg I, Bridey F, Figgie MP, Karila-Israel D, Haviland K, Mackenzie CR, Dimichele DM. Successful hip arthroplasty in an adult male with severe factor XI deficiency using Hemoleven(®), a factor XI concentrate. Haemophilia.
  20. Giampaolo A, Abbonizio F, Puopolo M, Arcieri R, Mannucci PM; Italian Association of Haemophilia Centres, Hassan HJ, Accorsi A, Ettorre PC, Schiavoni M, Palareti G, Rodorigo G, Valdré L, Amaddii G, Billio A, Notarangelo L, Iannacaro P, Muleo P, Biasioli C, Rossi V, Alatri A, Testa S, Vincenzi D, Scapoli G, Morfini M, Molinari AC, Lapecorella M, Mariani G, Baudo F, Caimi MT, Federici AB, Gringeri A, Mannucci PM, Santagostino E, Marietta M, Coppola A, Di Minno G, Perricone C, Schiavulli M, Miraglia E, Rocino A, Zanon E, Gagliano F, Mancuso G, Siragusa S, Rivolta F, Tagliaferri A, Gamba G, Iorio A, Oliovecchio E, Dragani A, Arbasi MC, Albertini P, Mancino A, Lombardo VT, Latella C, D'Incà M, Landolfi Raffaele, Biondo Francesca, Mazzucconi MG, Santoro Cristina, Mameli AL, Piseddu G, Schinco PC, Messina M, Rossetti G, Barillari G, Feola G, Franchini M, Gandini G, Castaman G, Rodeghiero F. Consumption of clotting factors in severe haemophilia patients undergoing prophylaxis and on-demand treatment in Italy. Transfus Med.
  21. Santoro C, Hsu F, Dimichele DM. Haemostasis prophylaxis using single dose desmopressin acetate and extended use epsilon aminocaproic acid for adenotonsillectomy in patients with type 1 von Willebrand disease. Haemophilia.
  22. Tagliaferri A, Di Perna C, Santoro C, Schinco P, Santoro R, Rossetti G, Coppola A, Morfini M, Franchini M; on behalf of the Italian Association of Hemophilia Centers.Cancers in Patients with Hemophilia: a Retrospective Study from the Italian Association of Hemophilia Centers. J Thromb Haemost.
  23. Biondo F, Matturro A, Santoro C, Leporace A, D'Elia G, Baldacci E, Pignoloni P, Pulsoni A, Foà R, Mazzucconi M. Remission of acquired von Willebrand syndrome after successful treatment of gastric MALT lymphoma. Haemophilia.
  24. Siboni SM, Mannucci PM, Gringeri A, Franchini M, Tagliaferri A, Ferretti M, Tradati FC, Santagostino E, von Mackensen S; Italian Association of Haemophilia Centres (AICE). Health status and quality of life of elderly persons with severe hemophilia born before the advent of modern replacement therapy. J Thromb Haemost. 2009; 7(5):780-6.
  25. Mannucci PM, Franchini M, Castaman G, Federici AB; AICE (Italian Association of Haemophilia Centres). Evidence-based recommendations on the treatment of von Willebrand disease in Italy.
  26. Rocca A, Pizzinelli S, Oliovecchio E, Santagostino E, Rocino A, Iorio A; Italian ad hoc study group. Replacement therapy with recombinant factor IX. A multicentre evaluation of current dosing practices in Italy. Blood Transfus.
  27. von Mackensen S, Gringeri A, Siboni SM, Mannucci PM; Italian Association Of Haemophilia Centres (AICE).Health-related quality of life and psychological well-being in elderly patients with haemophilia. Haemophilia.
  28. Baudo F, Collins P, Huth-Kühne A, Lévesque H, Marco P, Nemes L, Pellegrini F, Tengborn L, Knoebl P; EACH2 registry contributors. Management of bleeding in acquired hemophilia A: results from the European Acquired Haemophilia (EACH2) Registry. Blood.
  29. Collins P, Baudo F, Knoebl P, Lévesque H, Nemes L, Pellegrini F, Marco P, Tengborn L, Huth-Kühne A; EACH2 registry collaborators. Immunosuppression for acquired hemophilia A: results from the European Acquired Haemophilia Registry (EACH2). Blood.
  30. Knoebl P, Marco P, Baudo F, Collins P, Huth-Kühne A, Nemes L, Pellegrini F, Tengborn L, Lévesque H; EACH2 Registry Contributors. Demographic and clinical data in acquired hemophilia A: results from the European Acquired Haemophilia Registry (EACH2). J Thromb Haemost.
  31. Tengborn L, Baudo F, Huth-Kühne A, Knoebl P, Lévesque H, Marco P, Pellegrini F, Nemes L, Collins P; EACH2 registry contributors. Pregnancy-associated acquired haemophilia A: results from the European Acquired Haemophilia (EACH2) registry. BJOG.
  32. Santoro C, Baldacci E, Mercanti C, Mazzucconi MG Tailored versus Standard Dose Prophylaxis in Children with Hemophilia A. Semin Thromb Hemost.
  33. Coppola A, Santoro C, Franchini M, Mannucci C, Mogavero S, Molinari AC, Schinco P, Tagliaferri A, Santoro RC. Emerging Issues on Comprehensive Hemophilia Care: Preventing, Identifying, and Monitoring Age-Related Comorbidities. Semin Thromb Hemost.
  34. Santoro Cristina, Biondo Francesca, Baldacci Erminia, De Propris Maria Stefania, Guarini Anna, Paoloni Francesca, Foà Roberto, Mazzucconi Maria Gabriella. Rituximab in previously treated primary immune thrombocytopenia (pITP) patients: evaluation of short- and long-term efficacy and safety. Acta Haematol.
  35. Montanaro M, Latagliata R, Cedrone M, Spadea A, Rago A, Di Giandomenico J, Spirito F, Porrini R, De Muro M, Leonetti SC, Villivà N, De Gregoris C, Breccia M, Montefusco E, Santoro C, Cimino G, Majolino I, Mazzucconi MG, Alimena G, Andriani A. Thrombosis and survival in essential thrombocythemia: a regional study of 1,144 patients. Am J Hematol.
  36. Abbonizio F, Giampaolo A, Coppola A; Italian Association of Haemophilia Centres (AICE), Arcieri R, Hassan HJ. Therapeutic management and costs of severe haemophilia A patients with inhibitors in Italy.Haemophilia.
  37. Ruggeri M, Tosetto A, Palandri F, Polverelli N, Mazzucconi MG, Santoro C, Gaidano G, Lunghi M, Zaja F, De Stefano V, Sartori R, Fazi P, Rodeghiero F; The Gruppo Italiano Malattie EMatologiche dell'Adulto (GIMEMA) AnemiaThrombocytopenias Working Party. GIMEMA Study ITP0311. Thrombotic Risk In Patients With Primary Immune Thrombocytopenia Is Only Mildly Increased And Explained By Personal And Treatment-Related Risk Factors. J Thromb Haemost.
  38. Morfini M, Marchesini E, Paladino E, Santoro C, Zanon E, Iorio A. Pharmacokinetics of plasma-derived vs. recombinant FVIII concentrates: a comparative study. Haemophilia.
  39. Rocino A, Coppola A, Franchini M, Castaman G, Santoro C, Zanon E, Santagostino E, Morfini M; Italian Association of Haemophilia Centres (AICE) Working Party. Principles of treatment and update of recommendations for the management of haemophilia and congenital bleeding disorders in Italy. Blood Transfus.
  40. Santoro C, Di Mauro R, Baldacci E, De Angelis F, Abbruzzese R, Barone F, Bochicchio RA, Ferrara G, Guarini A, Foà R, Mazzucconi MG. Haemophilia.
  41. Liu Y, Zhang L, Santoro C, Song J, Rodriguez A, Wang L. Rituximab for treating inhibitors in people with inherited severe hemophilia. Cochrane Database Syst Rev.
  42. Tagliaferri A, Feola G, Molinari AC, Santoro C, Rivolta GF, Cultrera DB, Gagliano F, Zanon E, Mancuso ME, Valdré L, Mameli L, Amoresano S, Mathew P, Coppola A; POTTER Study Group. Benefits of prophylaxis versus on-demand treatment in adolescents and adults with severe haemophilia A: the POTTER study. Thromb Haemost.
  43. Civaschi E, Klersy C, Melazzini F, Pujol-Moix N, Santoro C, Cattaneo M, Lavenu-Bombled C, Bury L, Minuz P, Nurden P, Cid AR, Cuker A, Latger-Cannard V, Favier R, Nichele I, Noris P; European Haematology Association - Scientific Working Group on Thrombocytopenias and Platelet Function Disorders. Analysis of 65 pregnancies in 34 women with five different forms of inherited platelet function disorders. Br J Haematol.
  44. Asselta R, Robusto M, Platé M, Santoro C, Peyvandi F, Duga S. Molecular characterization of 7 patients affected by dys- or hypo-dysfibrinogenemia: Identification of a novel mutation in the fibrinogen Bbeta chain causing a gain of glycosylation. Thromb Res.
  45. Silvia Riva, Ilaria Cutica, Caspar Krampe, Laura Reinecke, William Russell-Edu, Cristina Santoro, Angiola Rocino, Elena Santagostino, vega rusconi, Gabriella Pravettoni .A cohort pilot study on HIV-associated neuropsychological impairments in haemophilia patients. Front Hum Neurosci.
  46. Franchini Massimo, Castaman Giancarlo, Coppola Antonio, Santoro Cristina, Zanon Ezio, Di Minno Giovanni, Morfini Massimo, Santagostino Elena, Rocino Angiola. Acquired Inhibitors of clotting factors: AICE recommendations for diagnosis and management. Blood Transfus. 2015 Jun 24:1-16.

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